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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASP9
All Species:
10
Human Site:
T125
Identified Species:
18.33
UniProt:
P55211
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P55211
NP_001220.2
416
46281
T125
P
E
V
L
R
P
E
T
P
R
P
V
D
I
G
Chimpanzee
Pan troglodytes
Q5IS54
277
31588
P18
K
S
I
K
N
L
E
P
K
I
I
H
G
S
Q
Rhesus Macaque
Macaca mulatta
XP_001082859
416
46192
T125
P
E
V
L
R
P
E
T
P
R
P
V
D
I
G
Dog
Lupus familis
XP_865164
414
45235
V124
P
Q
V
V
R
P
S
V
P
R
P
T
D
N
G
Cat
Felis silvestris
Mouse
Mus musculus
P29594
452
50642
S164
S
T
D
A
T
E
H
S
L
D
N
G
D
G
P
Rat
Rattus norvegicus
P55215
452
50709
S164
S
T
D
T
M
E
H
S
L
D
N
G
D
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520982
366
40213
A99
P
G
E
K
Q
G
M
A
I
K
V
Y
S
L
K
Chicken
Gallus gallus
Q98943
424
47941
S135
P
R
L
I
V
E
H
S
L
D
S
G
D
G
P
Frog
Xenopus laevis
P55866
282
32106
I23
D
A
K
E
Y
F
T
I
Q
P
R
S
L
Q
N
Zebra Danio
Brachydanio rerio
NP_001007405
436
48445
S136
L
V
P
L
R
P
E
S
L
P
V
H
K
T
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O02002
323
35908
M62
A
N
K
F
V
A
R
M
P
V
E
R
Y
A
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P42573
503
56598
S141
S
S
V
S
S
F
T
S
Y
Q
D
I
Y
S
R
Sea Urchin
Strong. purpuratus
XP_799258
437
48470
R129
V
P
L
V
W
P
A
R
D
S
T
G
D
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.8
93.9
76.9
N.A.
28.9
28.3
N.A.
52.8
31.1
22.6
47.2
N.A.
22.1
N.A.
21.6
32.2
Protein Similarity:
100
35.8
96.8
84.1
N.A.
46.9
46.2
N.A.
65.6
48.3
38.7
64.2
N.A.
35.8
N.A.
37.5
51
P-Site Identity:
100
6.6
100
60
N.A.
6.6
6.6
N.A.
6.6
13.3
0
26.6
N.A.
6.6
N.A.
6.6
13.3
P-Site Similarity:
100
13.3
100
73.3
N.A.
13.3
13.3
N.A.
26.6
33.3
0
33.3
N.A.
6.6
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
8
0
8
8
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
0
0
0
0
8
24
8
0
54
0
0
% D
% Glu:
0
16
8
8
0
24
31
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
16
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
8
0
0
0
0
0
31
8
24
24
% G
% His:
0
0
0
0
0
0
24
0
0
0
0
16
0
0
0
% H
% Ile:
0
0
8
8
0
0
0
8
8
8
8
8
0
16
0
% I
% Lys:
8
0
16
16
0
0
0
0
8
8
0
0
8
0
8
% K
% Leu:
8
0
16
24
0
8
0
0
31
0
0
0
8
8
0
% L
% Met:
0
0
0
0
8
0
8
8
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
16
0
0
8
8
% N
% Pro:
39
8
8
0
0
39
0
8
31
16
24
0
0
0
24
% P
% Gln:
0
8
0
0
8
0
0
0
8
8
0
0
0
8
8
% Q
% Arg:
0
8
0
0
31
0
8
8
0
24
8
8
0
0
8
% R
% Ser:
24
16
0
8
8
0
8
39
0
8
8
8
8
16
16
% S
% Thr:
0
16
0
8
8
0
16
16
0
0
8
8
0
8
0
% T
% Val:
8
8
31
16
16
0
0
8
0
8
16
16
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
8
0
0
8
16
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _